Author: Jennifer Chen Major: Biochemistry and Biology
Author: Jennifer Chen | Major: Biochemistry, Biology | Semester: Fall 2024
I have also had a profound interest in exploring the intricate biological responses to external stimuli or stressors, whether it’s deciphering host defense mechanisms against viruses like the myxoma virus or unraveling the development of metabolic disorders in response to dietary factors in Drosophila models. This fascination drives my research towards understanding the complex interplay between genetics, environment, and physiological responses in various biological systems.
With these interests in mind, I began investigating various professors’ research projects, leading me to discover Dr. Xuan Zhuang in the Department of Biological Sciences. Dr. Zhuang’s lab focuses on the genetic basis of biodiversity, the generation of genetic novelty, and the maintenance of this diversity. Using model organisms like Drosophila, her research delves into novel trait evolution, complex trait variation, and the underlying molecular mechanisms and evolutionary forces. Fascinated by these topics, I reached out to Dr. Zhuang at the end of my freshman year, expressing my desire to join her lab. One thing led to another, and I have now been a part of this lab for nearly two years, choosing to use my research here as the foundation for my honors thesis.
Through this journey, I have learned a great deal about my research topic and about myself. Delving into the genetic underpinnings of biodiversity and trait evolution has provided me with a deeper understanding of the complexity of biological systems. I have gained valuable insights into how genetic variations can lead to significant differences in trait expression and how these differences are preserved within populations. This experience has also taught me the importance of perseverance, attention to detail, and critical thinking.
However, my research journey was not without its challenges. One of the primary obstacles I faced was the steep learning curve associated with utilizing model organisms–Drosophila– for the first time, as well as new methodologies used in Dr. Zhuang’s lab. Initially, I struggled with understanding and executing complex experiments. To overcome this, I dedicated extra time to studying the relevant literature, seeking guidance from my mentor, and practicing the techniques until I became proficient. This experience taught me the value of resilience and the importance of seeking help when needed.
Dr. Zhuang played a pivotal role in my research journey. As my faculty mentor, she provided me with invaluable guidance, support, and encouragement. Her expertise and insights were instrumental in shaping my research project and helping me navigate the challenges I encountered. Additionally, other faculty members and students in the lab were incredibly helpful, offering their knowledge and assistance whenever I needed it.
One of the highlights of my research experience has been attending various research conferences, to present my research project. These opportunities allowed me to share our work with a broader scientific community, receive feedback from experts in the field, and network with other researchers. It was an enriching experience that further fueled my passion for scientific inquiry and research.
Looking ahead, I am excited about the possibilities that lie before me. I plan to dive into my commitment for translational medicine, and its real world impact, at medical school. This experience has solidified my desire to pursue a career in biomedical research, and I am eager to contribute to advancements in this field.